Office Depot (Paul Sakuma/AP Photo)

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Stores closed: 17 in 2009 and 2010*

Almost systematically, Office Depot, a Florida-based office supplier, has been declining in business since 2007. The recession has hurt, sure, but Office Depot's share price began to freefall beginning in May of '07, even before the downturn. Office Depot stock sold for just over $4 this week, a far cry from its $36.40 trading price in May 2007 — and it's been store closure after store closure all along the way. While Office Depot slashes as many as 100 U.S. stores per year these days, the supplier will have canned 17 of its Canadian locations between 2009 and 2010.

*Includes three planned closures later this year.

* Bing: Office Depot's stock freefall